NSAID-induced small bowel damage?
This is the gross appearance of a segment of jejunum in a patient who died at home; he had a history of taking NSAIDs for rheumatoid arthritis. We had just started our post-mortem study and were looking for evidence of NSAID-induced small bowel damage. (The prevalence of visually apparent non-steroidal anti-inflammatory drug induced small intestinal disease in man. N Engl J Med 1992, 327: 749-54.)
By an amazing coincidence, this patient was one of the first who underwent enteroscopy in the series of John Morris and John McKenzie, who were doing a study in parallel with our own post-mortem study. We thought we had identified the lesion. On histological examination this proved to be amyloid.
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