Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 20 February 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Gastric bypass complications could lead to memory loss

Weight loss surgery followed by frequent vomiting could lead to a condition resulting in memory loss, finds a US research published in Neurology and reported by the BBC this week.

News image

fiogf49gjkf04

Wernicke encephalopathy is a syndrome that affects the nervous system and brain.

This syndrome can lead to confusion and the inability to co-ordinate movement, and is caused by a lack of vitamin B1, or thiamine.

Drs Sonal Singh and Abhay Kumar from North Carolina found that frequent vomiting after surgery can lead to the syndrome.

The team performed a systematic review of MEDLINE, Embase, Ovid, Science Citation Index, and Google Scholar.

The team searched for case reports, case series, or cohort studies of Wernicke encephalopathy after bariatric surgery.

The researchers identified 32 cases of Wernicke encephalopathy after obesity surgery.

Of these, 27 were women.

Most patients had vomiting as a risk factor.

21 patients presented with the triad of Wernicke encephalopathy
Neurology

The team observed that 21 patients presented with the triad of Wernicke encephalopathy, which included confusion, ataxia, and nystagmus.

Optic neuropathy, papilledema, deafness, seizures, asterixis, weakness, and sensory and motor neuropathy were also reported.

The team state that it is not clear if the condition is more common in women, or if there were more cases in women as 75% of obesity surgery patients are female.

The team found the syndrome to occur within one to three months of weight loss surgery, such as gastric bypass surgery, although one case occurred 18 months after surgery.

The researchers urged those who had undergone weight loss surgery to take their prescribed vitamin supplements.

Patients should be alert for symptoms such as vomiting, confusion, visual changes and lack of co-ordination.

The team encouraged people who have had weight loss surgery and start experiencing any of these symptoms to see a doctor right away.

Dr Colin Waine, of the National Obesity Forum urged against avoidance of weight loss surgery, for those most in need.

Dr Waine commented, “The results of weight loss surgery can be very good.”

“Some people are so at risk that they are going to die from other causes without surgery.”

“The risk of encephalopathy is probably much less than the risk they are facing from obesity.”

“We clearly need to note this report, and must be aware of it, but I don't think it should lead to a knee-jerk rejection.”

Dr Singh and colleague conclude, “Wernicke encephalopathy after bariatric surgery usually occurs between 4 and 12 weeks postoperatively, especially in young women with vomiting.”

“If treated promptly, the outlook is usually good.”

“For treatment, patients are given vitamin B1 through an IV or injection.”

"We found that of the 32 people in the study, 13 made a full recovery, though others continued to have problems such as memory loss."

“More studies are needed to determine how often the syndrome occurs after weight loss surgery.”

BBC 2007: 13 March 2007, 00:16 GMT, Neurology 2007: 68: 807-11
15 March 2007

Go to top of page Email this page Email this page to a colleague

 20 February 2018 
Complications and surveillance colonoscopies
 20 February 2018 
Treatment algorithm for polyp cancers
 20 February 2018 
Predictors of postoperative infection in Crohn's
 19 February 2018 
Screening colonoscopy in the right and left colon
 19 February 2018 
NAFLD prevalence in the USA
 19 February 2018 
Fructans in children with IBS

 16 February 2018 
Undetected celiac in the elderly
 16 February 2018 
Inflammatory bowel diseases are global diseases
 16 February 2018 
Fructans induce non-celiac gluten sensitivity
 15 February 2018 
Oral direct-acting antiviral treatment for Hep C virus genotype 1
 15 February 2018 
NSAIDS and GI damage
 15 February 2018 
Primary vs secondary surgery for the presence of lymph node metastasis
 14 February 2018 
Management of hemorrhoids in the USA
 14 February 2018 
Predicting adenoma detection rate
 14 February 2018 
Normal bowel frequency characterization in the USA 
 13 February 2018 
Prebiotics improve endothelial dysfunction
 13 February 2018 
Personalising treatment options for IBS
 13 February 2018 
Diagnostic criteria for a Rome IV functional gastrointestinal disorders
 12 February 2018 
Visceral hypersensitivity and functional GI disorders
 12 February 2018 
Depression and aggressive IBD
 12 February 2018 
Variability in interpretation of endoscopic findings impacts patient management
 09 February 2018 
Treatment of choice for anastomotic stricture in IBD
 09 February 2018 
PRO measurement information system 
 09 February 2018 
Overall disease severity indices for IBD
 08 February 2018 
Prediction of endoscopically active disease

 08 February 2018 
Steroid-refractory acute severe ulcerative colitis
 08 February 2018 
Decision aid used by IBD patients
 07 February 2018 
Ursodeoxycholic acid combined with bezafibrate for itching
 07 February 2018 
Change in microbiome in gastritis vs gastric carcinoma
 07 February 2018 
Colorectal cancer and primary sclerosing cholangitis-IBD
 06 February 2018 
Risk of death after liver transplantation
 06 February 2018 
Crohn’s disease vs refractory pouchitis
 06 February 2018 
Support for functional dyspepsia symptom diary
 05 February 2018 
Helicobacter spp influence on GI tract 
 05 February 2018 
No link found between severe reflux and all-cause mortality 
 05 February 2018 
Psychological distress in PPI non-responders
 02 February 2018 
Assessing psychosexual impact of IBD
 02 February 2018 
Decrease in overall mortality with cholera vaccination
 02 February 2018 
Diagnostic performance of fecal immunochemical tests
 01 February 2018 
Screening frequency with family histories of colorectal cancer
 01 February 2018 
IBD and sport participation
 01 February 2018 
Life with a stoma 
 31 January 2018 
Aprepitant and gastroparesis 
 31 January 2018 
Anesthesia risk in colonoscopy
 31 January 2018 
GED-0301 for Crohn's Disease
 30 January 2018 
Intestinal dysbiosis and allergic diseases in infants
 30 January 2018 
Fructans and IBS symptoms in children
 29 January 2018 
Dosing calculator for therapy optimization in IBD
 29 January 2018 
Glecaprevir–pibrentasvir for in HCV
 29 January 2018 
Food allergen injections in eosinophilic esophagitis
 29 January 2018 
Reliability of the IBD index
 26 January 2018 
Tofacitinib vs biological therapies for ulcerative colitis
 26 January 2018 
Optimizing selection of biologics in IBD
 26 January 2018 
Nutritional risk and laparoscopic-assisted gastrectomy outcomes
 25 January 2018 
Patient-reported outcome measure for functional dyspepsia
 25 January 2018 
Predicting intra-abdominal infections after colorectal surgery
 25 January 2018 
Predictors of gastric cancer risk
 24 January 2018 
Risk factors underlying previously undiagnosed cirrhosis
 24 January 2018 
Ethnicity influences phenotype in IBD
 24 January 2018 
Bariatric surgery vs medical obesity treatment

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us