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 22 May 2018

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News

Co-morbidities reduce quality of life in celiac disease

Reduced health-related quality of life in celiac disease is associated with physical and mental comorbidities, shows the latest Alimentary Pharmacology & Therapeutics.

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Data available on predictors of reduced health-related quality of life in celiac disease are not consistent.

Dr Häuser and colleagues from Germany tested predictors of reduced health-related quality of life in celiac disease.

The team undertook a postal survey of 1000 adults with celiac disease of the German Celiac Society.

The subjects were asked to complete a medical and a sociodemographic questionnaire.

The subjects completed the Short-Form Health Survey, the Celiac Disease Questionnaire, and the Hospital Anxiety and Depression Scale.

The team tested predictors of reduced health-related quality of life by logistic regression analysis.

Physical comorbidities predict reduced mental summary scores
Alimentary Pharmacology & Therapeutics

The research team found that physical comorbidities were associated with reduced physical summary scores of the Short-Form 36.

The team noted that mental disorders were also associated with a reduced physical summary score of the Short-Form 36 questionnaire.

The team observed that mental disorders predicted a reduced mental summary score of the Short-Form 36.

In addition, physical comorbidities predicted a reduced mental summary score of the Short-Form 36.

Younger age at diagnosis predicted a reduced mental summary score of the Short-Form 36.

The team observed that mental disorder, and non-compliance with gluten-free diet was associated with reduced Celiac Disease Questionnaire scores.

Active medical comorbidities, and dissatisfaction with doctor-patient communication were associated with reduced scores.

Dr Häuser's team concludes, “Reduced health-related quality of life in celiac disease is associated with physical and mental comorbidities.”

“These factors are also associated with non-compliance with gluten-free diet and dissatisfaction with doctor-patient communication.”

Aliment Pharmacol Ther 2007: (5): 569-78
19 February 2007

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