It is unknown whether the improved survival seen at high-volume centers has been translated to all patients with pancreatic cancer.
Dr Taylor Riall and colleagues from Texas evaluated the Surveillance, Epidemiology, and End Results database.
The research team assessed the population-based trends in surgical resection and survival.
All patients diagnosed with pancreatic cancer from 1988 to 1999 were identified.
|2-year survival increased by 7% after surgical resection|
|Journal of Gastrointestinal Surgery|
The researchers compared the survival and proportion of patients undergoing surgical resection for each of 3 equal time periods.
There were 24,016 patients with pancreatic cancer.
The team noted that 19,533 had stage data available.
The researchers noted that 9% had localized, 29% had regional, and 62% had distant disease.
Resection rates increased for patients with localized and regional disease over the three time periods.
The team found that survival increased for patients with regional and distant disease.
For regional pancreatic cancer patients, 2-year survival increased from 10% to 14%.
The researchers observed that 2-year survival increased from 22% to 29% following surgical resection.
For resected local or regional pancreatic cancer, the year of diagnosis was and independent predictor of improved survival.
Dr Riall's team commented, “Surveillance, Epidemiology, and End Results patients with regional and distant pancreatic cancer have improved survival over the past decade in both unadjusted and adjusted models.”
“The improvement is most striking for patients with regional disease and reflects increased resection rates and improved resection techniques over time.”