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 24 May 2018

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News

Young hepatocellular carcinoma patients have poor early prognosis

Young hepatocellular carcinoma patients are more likely to have larger tumors that expire within 1 year than the older hepatocellular carcinoma patients, shows the latest Liver International.

News image

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Dr Sheng-Nan Lu and colleagues from Taiwan previously showed that male hepatocellular carcinoma patients below 40 years of age had the worst survival in the initial years.

These patients had the best prognosis thereafter.

Thus, it seems that age has a paradoxical influence on the prognosis.

To further clarify the issue of age on hepatocellular carcinoma prognosis, the research team conducted another study.

A total of 11,312 hepatocellular carcinoma cases from 7 medical centers from 1986 to 2002 were included.

The research team analyzed the 1-year survival and survival after 1 year.

90% of hepatocellular carcinoma were Hepatitis B carriers
Liver International

The team found that male gender, age younger than 40 years old and Hepatitis B virus were associated with worse 1-year survival.

In contrast, male gender, age younger than 40 years old and Hepatitis B were associated with better survival after 1 year.

The researchers observed that a higher percentage of the young hepatocellular carcinoma patients had a tumor size larger than 3 cm.

The team noted that 84% of hepatocellular carcinoma patients below 40 years of age were male, and 90% of them were Hepatitis B carriers.

Dr Lu's team concludes, “If we encountered a young hepatocellular carcinoma patient, the patient will probably be a male Hepatitis B carrier.”

“He would probably have larger tumor and is more likely to expire within 1 year than the older hepatocellular carcinoma patients.”

“However, if the young hepatocellular carcinoma patient can survive for more than 1 year, he would probably have better survival in the following years than the older patients.”

Liver Int 2006: 26(7): 766
25 August 2006

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