Dr Trottera and colleagues determined the role of liver biopsy and outcome of patients undergoing donor evaluation for adult-to-adult right hepatic lobe living donor liver transplantation.
The investigators reviewed records of patients presenting for a comprehensive donor evaluation between 1997 and 2005.
Liver biopsy was performed only in patients with risk factors for abnormal histology.
The investigative team noted that 260 patients underwent a comprehensive donor evaluation.
|44% of eligible patients fulfilled criteria for liver biopsy |
|American Journal of Transplantation|
Of these, 45% were suitable for donation, 5% did not complete evaluation ,and 50% were rejected.
The team found that 4 patients underwent unsuccessful hepatectomy surgery due to discovery of intraoperative abnormalities.
Between 1997 and 2001, the acceptance rate of donor candidates was 63%, higher than between 2002 and 2005, when it was 36%.
The investigators observed that 44% of eligible patients fulfilled criteria for liver biopsy and 42% had an abnormal finding.
Dr Trottera's team comments, “Less than half of the patients undergoing donor evaluation were suitable donors and the donor acceptance rate has declined over time.”
“A large proportion of the patients undergoing liver biopsy have abnormal findings.”
“Our evaluation process failed to identify 4 of 103 who had aborted donor surgeries.”