Hemorrhage is among the most serious complications of colorectal polypectomy and may occur after a longer postprocedure interval.
Dr Makoto Okamoto and colleagues from Japan elucidated the risk factors for delayed postpolypectomy hemorrhage.
The research team also evaluated polyp characteristics, and the general condition of the patients.
The researchers performed a total of 6617 cases of colorectal polypectomy in 3138 consecutive patients.
|Hypertension was a complication in 68% of cases|
The risk factors for delayed postpolypectomy hemorrhage were assessed among polyp characteristics, as well as the method of resection.
Patient conditions such as smoking, alcohol, hypertension, diabetes mellitus, and hyperlipidemia were compared between case-control pairs.
The controls were matched on polyp-related characteristics by conditional logistic regression.
Hemorrhage occurred in 38 lesions of 37 patients.
The researchers found that 22 required endoscopic hemostasis and 1 required blood transfusion.
Although polyp size was associated with the occurrence of delayed hemorrhage, the team noted that other polyp-related factors were not significant.
The researchers observed that hypertension was a complication in 68% of cases, and in 28% of matched controls.
Other patient characteristics were not significant.
The interval between polypectomy and hemorrhage was significantly longer in patients with hypertension than in those without hypertension.
Dr Okamoto's team concludes, “This study does not provide information regarding prevention of hemorrhage.”
“Hypertension is a significant risk factor for delayed colorectal postpolypectomy hemorrhage.”
“The interval between polypectomy and hemorrhage can be as long as 14 days in the presence of hypertension.”