In this study, doctors from Japan and the United States investigated the outcome of liver transplantation from donors who used cocaine.
The team evaluated 807 adult liver transplantations performed between 1994 and 2000. Of these, 72 donors were current cocaine users.
The doctors compared donor characteristics and post-transplantation outcomes between the cocaine group and 126 matched controls.
|Graft loss was higher in the cocaine group.|
They found that marijuana, opiates and amphetamines were also often used by donors in the cocaine group.
There was also a high incidence of acute alcohol use in the cocaine donor group.
The team found that graft loss within 3 months of transplant was significantly higher in the cocaine group than the controls (18% vs 9%).
Dr Teruo Komokata's team concluded, "Potential adverse effect of cocaine and substances concurrently involved on donor liver was suggested".
"To clarify the distinct acceptance criteria of cocaine users for liver donation, prospective study is warranted".