Researchers from Taiwan have conducted a study to investigate the impact of prophylactic antibiotics on postoperative infection complications in elective laparoscopic cholecystectomy.
The team evaluated a total of 277 patients.
At the time of induction of anesthesia patients in group A received 1 g cefazolin, while patients in group B acted as a control. Control patients received 10 ml isotonic sodium chloride solution.
The researchers compared the patients' characteristics and outcomes.
|The overall rate of infection was 1%.|
|American Journal of Surgery|
The team found that the overall rate of infection was 1%. There was no significant difference in infection complications between the 2 groups.
Furthermore, the team was unable to identify any risk factors contributing to infection complications.
Dr Wen-Tsan Chang's team concluded, "We do not recommend the use of prophylactic antibiotics in elective laparoscopic cholecystectomy because they will not decrease the already-low rate of postoperative infectious complications".