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 21 May 2018

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News

Fatigue is a major problem after liver transplantation

Physical fatigue is a major problem in patients after liver transplantation, and does not appear to improve over time, report researchers in this month's Liver Transplantation.

News image

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Fatigue is often experienced after liver transplantation.

Dr Rita van den Berg-Emons and colleagues from the Netherlands assessed the severity of fatigue in liver transplant recipients.

The team explored the nature of fatigue, and factors that may be associated with severity of fatigue after liver transplantation.

The research team included 96 patients up to 15 years after liver transplantation.

Severity of fatigue and nature of fatigue were assessed with the Fatigue Severity Scale, and the Multidimensional Fatigue Inventory, respectively.

66% of were fatigued, and 44% were severely fatigued
Liver Transplantation

Furthermore, age, gender, indication for transplantation, and time since transplantation were evaluated.

The team also assessed immunosuppressive medication, self-experienced disability, and health-related quality of life as potential associated factors.

The researchers found that 66% of all patients were fatigued, and 44% of all patients were severely fatigued.

Patients experienced physical fatigue with reduced activity rather than mental fatigue and reduced motivation.

Age, gender, self-experienced disabilities, and health related quality of life were factors that correlated with severity of fatigue.

Dr van den Berg-Emons' team concluded, “This study indicates that fatigue is a major problem in patients after liver transplantation, and no indications were found that complaints of fatigue improve over time.”

“Liver transplant recipients experience physical fatigue and reduced activity rather than mental fatigue and reduced motivation.”

“These findings have implications for the development of interventions needed to rehabilitate persons after liver transplantation.”

Liver Transplant 2006: 12(6): 928-33
29 May 2006

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