Estimation of graft volume is critical in living donor liver transplantation.
Dr Paolo Salvalaggio and colleagues examined the accuracy of formula-derived graft volume estimates.
The investigators compared them to both radiogically-derived estimates and actual measurements.
The investigative team first compared formula-derived estimates of graft volume with actual volumes.
The team provided estimates for both right lobe and left lateral segment graft volume and applied these formulae to a validation cohort.
| Formula-derived calculations had lower error ratios than radiologic estimates|
Finally, the team evaluated both formula-derived and radiologically-derived estimates by comparing them to actual graft volume measurements.
There is a marginal concordance between formula-derived calculation and graft volume for right lobe donors.
However, the investigators noted that the error ratio was lower than for radiologic estimates.
In contrast, magnetic resonance imaging measurements for left later segment grafts demonstrated a lower error ratio than formula-derived estimation.
Dr Salvalaggio's team concluded, “Formula-derived estimates of graft volume should be routinely used in the initial screening of potential living donors as long as their limitations are appreciated.”