Barrett's esophagus is traditionally considered a disease of older white men.
Dr Gary Falk and colleagues from Ohio compared the demographic features of Barrett's esophagus in men and women.
The research team determined the prevalence and incidence of high-grade dysplasia and cancer in these patients.
All patients enrolled in the Cleveland Clinic Barrett's Esophagus Registry from 1979 to 2002 were studied.
The team compared age, ethnicity, number of endoscopies, hiatal hernia size, and length of Barrett's segment between men and women.
The researchers also compared the prevalence and incidence of high-grade dysplasia and cancer between men and women.
|The incidence rate was 1 in 179 patient-years of follow-up for women|
|Clinical Gastroenterology & Hepatology|
The team studied 839 patients in the registry, of which 628 were men and 211 were women.
Barrett's segment length was greater in men than in women.
The team found no significant differences for other parameters.
There were 114 prevalence cases of high-grade dysplasia or cancer, of which 96 men and 18 were women.
The researchers observed that women were less likely to have prevalent high-grade dysplasia or cancer than men.
There were 13 incidence cases of high-grade dysplasia or cancer, of which 11 were men and 2 were women during a mean follow-up of 5 years.
The team noted that the incidence rate was 1 in 179 patient-years of follow-up for women and 1 in 91 patient-years of follow-up in men.
Dr Falk's team commented, “25% of patients in our registry are women.”
“The length of Barrett's esophagus is greater in men than in women, but other features are similar.”
“The prevalence of high-grade dysplasia/cancer in women is approximately half that of men.”
“Incidence rates for high-grade dysplasia/cancer are similar in men and women, although the number of cases is small.”