Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 19 February 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Capsule endoscopy superior to push enteroscopy in GI bleeds

Capsule endoscopy is superior to push enteroscopy and small bowel barium radiography for diagnosing clinically significant small bowel pathology in gastrointestinal bleeding, reports November's American Journal of Gastroenterology.

News image

fiogf49gjkf04

Capsule endoscopy has a superior ability to examine the entire small bowel mucosa.

Therefore, it has broadened the diagnostic evaluation of patients with obscure gastrointestinal bleeding.

Published studies have revealed a numerically superior performance of capsule endoscopy.

Capsule endoscopy has a superior performance in determining a source of obscure gastrointestinal bleeding compared with other modalities.

However, due to small sample sizes, the overall magnitude of benefit is unknown.

Additionally, the types of lesions more likely to be found by capsule endoscopy versus alternate modalities are also unknown.

Dr Sharma Virender and colleagues evaluated the yield of small bowel findings with capsule endoscopy in obscure gastrointestinal bleeding.

The researchers compared these findings to other modalities using meta-analysis.

The research team performed a recursive literature search of prospective studies.

Incremental yield of capsule endoscopy for clinically significant findings is 30% with a number needed to treat of 3
American Journal of Gastroenterology

The studies included in the analysis compared the yield of capsule endoscopy to other modalities for obscure gastrointestinal bleeding.

Data on yield and types of lesions identified among various modalities were extracted, pooled, and analyzed.

The team calculated incremental yield and 95% confidence intervals of capsule endoscopy over comparative modalities.

A total of 14 studies with 396 participants compared the yield of capsule endoscopy with push enteroscopy for obscure gastrointestinal bleeding.

The researchers found that the yield for capsule endoscopy and push enteroscopy was 63% and 28%, respectively.

The yield for capsule endoscopy and push enteroscopy with clinically significant findings in 379 participants was 56% and 26%, respectively.

The team noted 3 studies with 88 participants that compared the yield of capsule endoscopy to small bowel barium radiography.

The yield for capsule endoscopy and small bowel barium radiography for any finding was 67% and 8%, respectively.

For clinically significant findings, the yield for capsule endoscopy and small bowel barium radiography for any finding was 42% and 6%, respectively.

The research team observed that the number needed to test to yield 1 additional clinically significant finding with capsule endoscopy over either modality was 3.

The team found the studies compared the yield of significant findings on capsule endoscopy to intraoperative enteroscopy, and computed tomography enteroclysis.

These studies also compared the yield of findings on capsule endoscopy to mesenteric angiogram, and small bowel magnetic resonance imaging.

The researchers noted that 10 of the 14 trials comparing capsule endoscopy with push enteroscopy classified the types of lesions found on examination.

Capsule endoscopy had a 36% yield for vascular lesions versus 20% for push enteroscopy, with an incremental yield of 16%.

The team observed inflammatory lesions in 11% with capsule endoscopy vs 2% with push enteroscopy, with an incremental yield of 9%.

There was no significant difference in the yield of tumors or ‘other' findings between capsule endoscopy and push enteroscopy.

Dr Virender's team concludes, “Capsule endoscopy is superior to push enteroscopy and small bowel barium radiography for diagnosing clinically significant small bowel pathology in patients with obscure gastrointestinal bleeding.”

“In study populations, the incremental yield of capsule endoscopy over push enteroscopy and small bowel barium radiography for clinically significant findings is 30% with a number needed to treat of 3.”

“This is primarily due to visualization of additional vascular and inflammatory lesions by capsule endoscopy.”

Am J Gastroenterol 2005: 100(11): 2407
01 November 2005

Go to top of page Email this page Email this page to a colleague

 19 February 2018 
Screening colonoscopy in the right and left colon
 19 February 2018 
NAFLD prevalence in the USA
 19 February 2018 
Fructans in children with IBS

 16 February 2018 
Undetected celiac in the elderly
 16 February 2018 
Inflammatory bowel diseases are global diseases
 16 February 2018 
Fructans induce non-celiac gluten sensitivity
 15 February 2018 
Oral direct-acting antiviral treatment for Hep C virus genotype 1
 15 February 2018 
NSAIDS and GI damage
 15 February 2018 
Primary vs secondary surgery for the presence of lymph node metastasis
 14 February 2018 
Management of hemorrhoids in the USA
 14 February 2018 
Predicting adenoma detection rate
 14 February 2018 
Normal bowel frequency characterization in the USA 
 13 February 2018 
Prebiotics improve endothelial dysfunction
 13 February 2018 
Personalising treatment options for IBS
 13 February 2018 
Diagnostic criteria for a Rome IV functional gastrointestinal disorders
 12 February 2018 
Visceral hypersensitivity and functional GI disorders
 12 February 2018 
Depression and aggressive IBD
 12 February 2018 
Variability in interpretation of endoscopic findings impacts patient management
 09 February 2018 
Treatment of choice for anastomotic stricture in IBD
 09 February 2018 
PRO measurement information system 
 09 February 2018 
Overall disease severity indices for IBD
 08 February 2018 
Prediction of endoscopically active disease

 08 February 2018 
Steroid-refractory acute severe ulcerative colitis
 08 February 2018 
Decision aid used by IBD patients
 07 February 2018 
Ursodeoxycholic acid combined with bezafibrate for itching
 07 February 2018 
Change in microbiome in gastritis vs gastric carcinoma
 07 February 2018 
Colorectal cancer and primary sclerosing cholangitis-IBD
 06 February 2018 
Risk of death after liver transplantation
 06 February 2018 
Crohn’s disease vs refractory pouchitis
 06 February 2018 
Support for functional dyspepsia symptom diary
 05 February 2018 
Helicobacter spp influence on GI tract 
 05 February 2018 
No link found between severe reflux and all-cause mortality 
 05 February 2018 
Psychological distress in PPI non-responders
 02 February 2018 
Assessing psychosexual impact of IBD
 02 February 2018 
Decrease in overall mortality with cholera vaccination
 02 February 2018 
Diagnostic performance of fecal immunochemical tests
 01 February 2018 
Screening frequency with family histories of colorectal cancer
 01 February 2018 
IBD and sport participation
 01 February 2018 
Life with a stoma 
 31 January 2018 
Aprepitant and gastroparesis 
 31 January 2018 
Anesthesia risk in colonoscopy
 31 January 2018 
GED-0301 for Crohn's Disease
 30 January 2018 
Intestinal dysbiosis and allergic diseases in infants
 30 January 2018 
Fructans and IBS symptoms in children
 29 January 2018 
Dosing calculator for therapy optimization in IBD
 29 January 2018 
Glecaprevir–pibrentasvir for in HCV
 29 January 2018 
Food allergen injections in eosinophilic esophagitis
 29 January 2018 
Reliability of the IBD index
 26 January 2018 
Tofacitinib vs biological therapies for ulcerative colitis
 26 January 2018 
Optimizing selection of biologics in IBD
 26 January 2018 
Nutritional risk and laparoscopic-assisted gastrectomy outcomes
 25 January 2018 
Patient-reported outcome measure for functional dyspepsia
 25 January 2018 
Predicting intra-abdominal infections after colorectal surgery
 25 January 2018 
Predictors of gastric cancer risk
 24 January 2018 
Risk factors underlying previously undiagnosed cirrhosis
 24 January 2018 
Ethnicity influences phenotype in IBD
 24 January 2018 
Bariatric surgery vs medical obesity treatment
 23 January 2018 
Atrophic gastritis after H. pylori eradication
 23 January 2018 
Ectopic pregnancy in women with IBD
 23 January 2018 
Celiac disease in IBS in the USA

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us