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 24 May 2018

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News

Socio-economic deprivation impacts on gastric cancer

Socio-economic deprivation is associated with longer diagnostic delay, greater operative mortality and a shorter duration of survival following R0 gastrectomy, finds the latest Scandanavian Journal of Gastroenterology.

News image

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Socio-economic deprivation has an influence on the outcome for patients diagnosed with breast, colorectal and bronchial cancer.

However, there are few data on its association with gastric cancer.

Dr Michael Stephens and colleagues from England determined the outcomes of socio-economic deprivation for patients with gastric cancer.

The investigative team studied 330 consecutive patients with gastric adenocarcinoma presenting to a single hospital between 1995 and 2004.

Deprivation scores were calculated using the National Assembly for Wales Indices of Multiple Deprivation.

5-year survival for patients from the most deprived areas was 32% vs 66% in the least deprived
Scandanavian Journal of Gastroenterology

The investigators subdivided the patients into quintiles for analysis.

The team found that inhabitants of the most deprived areas, in quintile 5, were younger at presentation, when compared with the least deprived areas.

These patients also experienced longer delays in diagnosis.

The investigators observed that operative mortality was 3-fold higher for patients from the most deprived areas when compared with less deprived areas.

There was no correlation between stage of disease and socio-economic deprivation.

For patients undergoing potentially curative surgery, the team noted that the 5-year survival for patients from the most deprived areas was 32%.

The team compared this to patients from the least deprived areas, for which the 5-year survival rate was 66%.

Dr Stephens' team commented, “Socio-economic deprivation was associated with younger age at diagnosis, longer diagnostic delay, greater operative mortality and a shorter duration of survival following R0 gastrectomy.”

“These poorer outcomes were not explained by the stage of disease at diagnosis.”

Scand J Gasroenterol 2005: 40(11): 1352-7
25 October 2005

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