Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 23 February 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Early prognostic tool for acute pancreatitis

Computed tomography severity index is a prognostic tool for complications and mortality, and can be used to indicate safe discharge from the intensive care unit, reports October's Journal of the American College of Surgeons.

News image

fiogf49gjkf04

Acute pancreatitis is a severe disease with unpredictable course and outcomes.

It is especially hard to identify early those patients who will have a fulminant course.

In a prospective observational study, Dr Vriens and colleagues assessed the computed tomography severity index.

The research team established the severity index within 48 hours after admission.

A computed tomography severity index of 0 to 3 had a 2% mortality rate
Journal of the American College of Surgeons

The team assessed whether the severity index is prognostic for morbidity and mortality.

The team also considered whether the index can predict the necessity for admission to an intensive care unit.

From 1994 to 2002, all patients with first time acute pancreatitis underwent spiral computed tomography with intravenous contrast within 48 hours of admission.

The extent of inflammation and necrosis was assessed to define the computed tomography severity index.

Patients were initially managed in an intensive care unit in a standardized fashion, and complications and mortality were registered in a systematic manner.

The research team reported that 79 patients were admitted with acute pancreatitis.

The researchers found that the overall complication rate was 57%, and mortality was 9%.

In patients with a computed tomography severity index of 0 to 3, these rates were 42% and 2%, respectively.

The team noted that in those with a computed tomography severity index of 4 to 6, the complication and mortality rates were 81% and 19%, respectively.

The researchers observed that in those with a severity index of 7 to 10, the complication and mortality rates were 100% and 33%, respectively.

Outcomes of subsequent computed tomography scans did not alter the initial prognosis.

The research team noted that an early computed tomography severity index correlated well with the incidence of complications.

The researchers also noted that sepsis, mortality, and necessity for intensive care admission was correlated with an early computed tomography severity index.

Dr Vriens' team concluded, “Acute pancreatitis is associated with marked morbidity and mortality.”

“Initial admission to an intensive care unit and standardized conservative treatment are justified for all patients.”

“Early establishment of the computed tomography severity index is an excellent prognostic tool for complications and mortality.”

“Patients with a computed tomography severity index of 0 to 3 can safely be discharged from the intensive care unit.”

J Am Coll Surg 2005: 201(4): 497-502
30 September 2005

Go to top of page Email this page Email this page to a colleague

 23 February 2018 
MRI and NAFLD
 23 February 2018 
Heavy metals on a gluten-free diet
 23 February 2018 
Patients on antithrombotic agents undergoing emergency and elective endoscopy
 22 February 2018 
Autophagy enhancers
 22 February 2018 
Outcomes with Crohn’s after infliximab withdrawal
 22 February 2018 
Elderly onset of IBD

 21 February 2018 
Adalimumab and infliximab in biologic-naïve Crohn's
 21 February 2018 
Cystic fibrosis and colorectal cancer
 21 February 2018 
Management of hemorrhoids in the USA
 20 February 2018 
Treatment algorithm for polyp cancers
 20 February 2018 
Predictors of postoperative infection in Crohn's
 20 February 2018 
Complications and surveillance colonoscopies
 19 February 2018 
Screening colonoscopy in the right and left colon
 19 February 2018 
NAFLD prevalence in the USA
 19 February 2018 
Fructans in children with IBS

 16 February 2018 
Undetected celiac in the elderly
 16 February 2018 
Inflammatory bowel diseases are global diseases
 16 February 2018 
Fructans induce non-celiac gluten sensitivity
 15 February 2018 
NSAIDS and GI damage
 15 February 2018 
Oral direct-acting antiviral treatment for Hep C virus genotype 1
 15 February 2018 
Primary vs secondary surgery for the presence of lymph node metastasis
 14 February 2018 
Predicting adenoma detection rate
 14 February 2018 
Normal bowel frequency characterization in the USA 
 13 February 2018 
Personalising treatment options for IBS
 13 February 2018 
Prebiotics improve endothelial dysfunction
 13 February 2018 
Diagnostic criteria for a Rome IV functional gastrointestinal disorders
 12 February 2018 
Visceral hypersensitivity and functional GI disorders
 12 February 2018 
Depression and aggressive IBD
 12 February 2018 
Variability in interpretation of endoscopic findings impacts patient management
 09 February 2018 
Treatment of choice for anastomotic stricture in IBD
 09 February 2018 
PRO measurement information system 
 09 February 2018 
Overall disease severity indices for IBD
 08 February 2018 
Prediction of endoscopically active disease

 08 February 2018 
Steroid-refractory acute severe ulcerative colitis
 08 February 2018 
Decision aid used by IBD patients
 07 February 2018 
Ursodeoxycholic acid combined with bezafibrate for itching
 07 February 2018 
Change in microbiome in gastritis vs gastric carcinoma
 07 February 2018 
Colorectal cancer and primary sclerosing cholangitis-IBD
 06 February 2018 
Risk of death after liver transplantation
 06 February 2018 
Crohn’s disease vs refractory pouchitis
 06 February 2018 
Support for functional dyspepsia symptom diary
 05 February 2018 
Helicobacter spp influence on GI tract 
 05 February 2018 
No link found between severe reflux and all-cause mortality 
 05 February 2018 
Psychological distress in PPI non-responders
 02 February 2018 
Assessing psychosexual impact of IBD
 02 February 2018 
Decrease in overall mortality with cholera vaccination
 02 February 2018 
Diagnostic performance of fecal immunochemical tests
 01 February 2018 
Screening frequency with family histories of colorectal cancer
 01 February 2018 
IBD and sport participation
 01 February 2018 
Life with a stoma 
 31 January 2018 
Aprepitant and gastroparesis 
 31 January 2018 
Anesthesia risk in colonoscopy
 31 January 2018 
GED-0301 for Crohn's Disease
 30 January 2018 
Intestinal dysbiosis and allergic diseases in infants
 30 January 2018 
Fructans and IBS symptoms in children
 29 January 2018 
Dosing calculator for therapy optimization in IBD
 29 January 2018 
Glecaprevir–pibrentasvir for in HCV
 29 January 2018 
Food allergen injections in eosinophilic esophagitis
 29 January 2018 
Reliability of the IBD index
 26 January 2018 
Tofacitinib vs biological therapies for ulcerative colitis

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us