Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 24 May 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Impact of race and ethnicity on IBD

The most recent issue of the American Journal of Gastroenterology shows that there are significant differences in IBD subtypes and serologic markers among racial/ ethnic groups with IBD in the United States.

News image

fiogf49gjkf04

Inflammatory bowel disease (IBD) is now increasingly recognized in diverse ethnic populations.

In the United States, IBD among the minority populations, especially Mexican Americans, has not been extensively studied.

The are the known genetic influences that differ among the IBD subtypes, including ulcerative colitis and Crohn's disease.

Serologic markers may differentiate ulcerative colitis and Crohn's disease.

Serologic markers also differentiate perinuclear antineutrophilic cytoplasmic antibody and anti-Saccharomyces cerevisiae antibody in ulcerative colitis and Crohn's disease.

Dr Joseph Sellin and colleagues from Texas determined whether there were significant differences among racial or ethnic groups.

The investigators included 148 patients with IBD seen in a university gastroenterology practice between 1999 and 2003.

African Americans with Crohn's had a higher incidence of IBD-associated arthritis
The American Journal of Gastroenterology

The team reported that Whites comprised 40%, African Americans 37%, Mexican Americans 20%, and Asians 3% of the total IBD patients.

The investigators found that African Americans and Whites predominantly had Crohn's disease.

The team noted that Mexican Americans predominantly had ulcerative colitis.

There was no difference between African Americans when compared to whites in terms of intestinal manifestations of Crohn's disease.

The investigators also observed no difference between Mexican Americans compared to whites in terms of intestinal manifestations of ulcerative colitis.

However, African Americans with Crohn's disease had a significantly higher incidence of IBD-associated arthritis.

The team noted that African Americans with Crohn's had a higher incidence of ophthalmological manifestations, notably uveitis, compared to whites with Crohn's.

Among ulcerative colitis patients, in comparison to the Mexican Americans, whites had significantly higher incidences of joint symptoms and osteoporosis.

The investigative team noted that whites had a stronger family history of IBD and colorectal carcinoma compared to the other ethnic groups.

Perinuclear antineutrophilic cytoplasmic antibody served as a sensitive marker for ulcerative colitis among Mexican Americans.

All the Mexican American patients with ulcerative colitis tested had positive perinuclear antineutrophilic cytoplasmic antibody vs 40% of whites.

Dr Sellin's team concludes, “There are significant differences in IBD subtypes and serologic markers among racial/ ethnic groups with IBD in the United States.”

Am J Gastroenterol 2005: 100(10) 2254
26 September 2005

Go to top of page Email this page Email this page to a colleague

 24 May 2018 
Precision medicine for tumors
 24 May 2018 
Patient-reported outcome measures in IBD trials
 24 May 2018 
Alcohol consumption and outcomes in drug-induced liver injury
 23 May 2018 
High body mass index is and ulcerative colitis
 23 May 2018 
Management of perianal fistulas in Crohn’s disease
 23 May 2018 
Cardiovascular risk in diabetes mellitus with NAFLD
 22 May 2018 
Worldwide H.pylori prevalence
 22 May 2018 
PPI and risk of stroke
 22 May 2018 
Online tool predicts bowel dysfunction severity prior to anterior resection
 21 May 2018 
Fecal incontinence and quality of life in IBD
 21 May 2018 
PPI use and cognitive decline
 21 May 2018 
Depressive symptoms in IBD youth
 18 May 2018 
Esophageal dilatation in clinical practice 
 17 May 2018 
IBD and later extraintestinal manifestations
 17 May 2018 
Repeat stool DNA testing
 17 May 2018 
IBS and chronic fatigue following GI infection
 16 May 2018 
Factors associated with fecal incontinence
 16 May 2018 
Diagnostic delay in Crohn's disease
 16 May 2018 
Cardiovascular risk in diabetes mellitus with NAFLD
 15 May 2018 
Guidelines for management of Crohn's
 15 May 2018 
New therapies for CDI
 15 May 2018 
Hep B in the Grey Zone
 14 May 2018 
Blood test for the diagnosis of fibrotic NASH
 14 May 2018 
Outcomes at bariatric centers of excellence
 14 May 2018 
Management of perianal fistulas in Crohn’s
 11 May 2018 
Detection of undiagnosed celiac disease
 11 May 2018 
Alcohol consumption and drug-induced liver injury
 10 May 2018 
Colorectal cancer screening
 10 May 2018 
Post‐operative complications in elderly IBD
 10 May 2018 
Fibrosis in patients with chronic hepatitis B
 09 May 2018 
Esophageal dilatation in clinical practice 
 09 May 2018 
Fecal incontinence
 09 May 2018 
Health problems and IBS
 07 May 2018 
Omitting antibiotics in uncomplicated acute diverticulitis
 07 May 2018 
Health problems and IBS
 07 May 2018 
Assessment of diminutive colorectal polyps
 04 May 2018 
Factors associated with fecal incontinence
 04 May 2018 
National Institutes of Health workshop and obesity
 04 May 2018 
Colorectal cancer screening and ethnic inequities
 03 May 2018 
Gastrointestinal ultrasound in IBD
 03 May 2018 
Ultransonography in postsurgical recurrence in Crohn's
 02 May 2018 
Hep C antiviral treatment and liver cancer risk
 02 May 2018 
Symptom assessment in cirrhotic ascites
 02 May 2018 
Chronic Hep B
 01 May 2018 
European guidelines on pancreatic cystic neoplasms
 01 May 2018 
Interferon‐free regimens in Hep C
 01 May 2018 
Age at IBD onset and extraintestinal complications
 30 April 2018 
Formula for preterm infants
 30 April 2018 
Primary antibiotic resistance and sequential therapy for H. pylori
 27 April 2018 
Eastern and western practices for endoscopic resection of colorectal lesions
 27 April 2018 
Anxiety scale for chronic esophageal disease
 27 April 2018 
Disease activity in eosinophilic esophagitis
 26 April 2018 
Obesity and physical activity in diverticulosis
 26 April 2018 
Primary sclerosing cholangitis in the USA
 25 April 2018 
Aspirin and pancreatic cancer
 25 April 2018 
Central mediators of irinotecan-induced steatohepatitis
 25 April 2018 
Neuroimaging in Hep C
 24 April 2018 
Scoring system identifies cancer risk in Barrett's
 24 April 2018 
Microbiome in athletes vs sedentary subjects
 23 April 2018 
Genome-wide study on HBV-related acute-on-chronic liver failure

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us