Dr Lewis and Dr Scott previously published guidelines for managing osteoporosis in celiac disease.
These guidelines recommended bone mineral density measurement at diagnosis.
The investigative team analyzed the results of following these guidelines in a district general hospital with a view to rationalizing screening.
The team reported that 43 consecutive patients with newly diagnosed celiac disease had dual-energy X-ray absorptiometry scans of the hip and lumbar spine.
| Osteoporosis at the hip and spine occurred in 7% and 14% of patients, respectively |
|European Journal of Gastroenterology & Hepatology|
Results were correlated with factors that were suspected to influence bone mineral density and were compared with comparable published studies.
The investigators found osteoporosis at the hip and spine in only 7% and 14% of patients, respectively.
The team noted that mean z scores were not significantly reduced.
Bone mineral density did not correlate with the duration of gluten exposure, symptoms, degree of villous atrophy, or smoking.
The investigators observed a significant correlation between bone mineral density and the body mass index at the hip but not at the spine.
Dr Lewis and colleague commented, “There is a surprisingly low yield of reduced bone mineral density, and doubt about increased fracture rates in celiac patients.”
“This does not support the current recommendations for screening bone mineral density at diagnosis, and the guidelines should be changed.”