Medical and surgical treatments are able to improve symptoms in patients with gastroesophageal reflux disease (GERD).
Dr Ciovica and colleagues from Austria evaluated the outcome following laparoscopic antireflux surgery in GERD patients with primary respiratory-related symptoms.
|All respiratory symptoms were significantly improved after surgery|
|Journal of Gastrointestinal Endoscopy|
The researchers also investigated the quality of life index before and after therapy.
The team reported that 338 consecutive patients underwent surgical treatment for GERD-induced symptoms.
Of this group 126 patients had primary respiratory symptoms related to GERD.
The researchers reported that all patients were studied by means of a symptom questionnaire, endoscopy, esophageal manometry, 24-hour esophageal pH monitoring, and a barium esophagogram.
All patients had medical therapy with proton pump inhibitors preoperatively and laparoscopic fundoplication was performed in all patients.
The researchers assessed the outcome 3 and 12 months postoperatively.
The team measured the quality of life by the means of the Gastrointestinal Quality of Life Index.
Following surgery, the research team found that all respiratory symptoms were significantly improved.
The investigators found that while Gastrointestinal Quality of Life Index was highly impaired before surgical therapy, a significant improvement of quality of life was obtained.
Dr Ciovica’s team concluded, “Because medical treatment is likely to fail in GERD patients with respiratory symptoms, the need for surgery arises and may be the only successful treatment in the long term.”
“Quality of life was significantly improved by surgical treatment.”