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 25 May 2018

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News

Determinants of life satisfaction in Crohn's and ulcerative colitis

Psychiatric and medical comorbidity and disease activity were risk factors of reduced health-related life satisfaction in Crohn's disease, whereas in ulcerative colitis, only disease activity predicted reduced health-related life satisfaction, reports this month's issue of Inflammatory Bowel Diseases.

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In patients with Crohn's disease and ulcerative colitis, medical, sociodemographic, and psychologic "risk and protective" factors for general and health-related life satisfaction have not been studied to date.

Psychologic factors for general and health-related life satisfaction are defined as preference-based judgments of general and health-related quality of life.

Dr Janke and colleagues included a total of 429 of 868 (49%) outpatients from 3 tertiary care centers where 317 had Crohn’s disease and 112 had ulcerative colitis.

The research team had the outpatients and members of the German Crohn's Disease/Ulcerative Colitis Foundation complete the sociodemographic and medical questionnaires.

The medical questionnaires included the German "Competence Network Inflammatory Bowel Diseases," the Hospital Anxiety and Depression Scale, and the "Questions on Life Satisfaction Modules".

The investigators assessed disease activity by the German Inflammatory Bowel Disease Activity Index.

Mental disorder was a risk factor of reduced general life-related satisfaction in Crohn’s disease and ulcerative colitis
Inflammatory Bowel Diseases

The team compared “Questions on Life Satisfaction Modules" data with a representative sample of the German general population.

The investigators found that general life-related satisfaction and health-related life satisfaction were reduced compared with the general German population.

In addition, the investigative team used logistic regression to show that mental disorder was a risk factor of reduced general life-related satisfaction in Crohn’s disease and ulcerative colitis.

The researchers noted that membership in a self-help organization offered no protection against reduced general life-related satisfaction in Crohn’s disease.

The team concluded that in Crohn’s disease, psychiatric and medical comorbidity and disease activity were risk factors of reduced health-related life satisfaction, whereas in ulcerative colitis, only disease activity predicted reduced health-related life satisfaction.

Dr Janke concludes, “To improve general life-related satisfaction and health-related life satisfaction in inflammatory bowel disease, both the treatment of bowel disease and medical and psychiatric comorbidity are necessary.”

“Strengthening of social support is an additional way to promote general life-related satisfaction."

Inflammatory Bowel Diseases 2005: 11(3):272-286
03 March 2005

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