Dr Caspari and colleagues from Bonn, Germany conducted a study to compare the diagnostic yields of magnetic resonance imaging (MRI) and capsule endoscopy for the detection of small-bowel polyps in patients with inherited polyposis syndromes.
The researchers performed MRI in 20 patients, with either Peutz-Jeghers’ syndrome (PJS; n = 4) or familial adenomatous polyposis (FAP; n = 16).
The researchers oversaw capsule endoscopy which was done the next day.
|Capsule endoscopy detected 448 polyps ranging from 1 to 30 mm in size in 8 different patients.|
The research team analyzed the number, size, and location of polyps.
Overall, the researchers detected 448 polyps ranging from about 1 mm to 30 mm in size in 8 patients by capsule endoscopy.
However, the research team noted that with MRI only 24 polyps all bigger than 5 mm could be seen in the 4 PJS patients.
Dr Caspari concluded, "Polyps bigger than 15 mm were detected similarly with capsule endoscopy and MRI, whereas smaller polyps were seen much more often with capsule endoscopy."
"Polyps smaller than 5 mm were exclusively seen with capsule endoscopy."
"However, location of the detected polyps and determination of their exact sizes was more accurate by MRI."