The postprandial increase of gastroesophageal reflux is caused largely by an increase in the rate of transient lower esophageal sphincter relaxations. Gastric distension is believed to be the most important contributing factor.
In this study, physicians from South Carolina, USA, determined the impact of rapid food intake on gastroesophageal reflux in 20 healthy volunteers.
The team used combined multichannel intraluminal impedance and pH (MII-pH) testing to record both acid and nonacid reflux.
On 2 separate days the physicians instructed the participants to eat the same standard meal within 5 minutes and 30 minutes in random order.
| The increase was predominantly in nonacid reflux.|
|American Journal of Hepatology|
The team recorded acid and nonacid reflux episodes during a 2-hour postprandial period.
The physicians found that the intake of a standard meal within 5 min was associated with more reflux episodes than an intake within 30 min.
The increase was confined to the first postprandial hour and was caused predominantly by an increase of nonacid reflux.
The team found that 45% of reflux events during the first postprandial hour were nonacid, compared with 22% during the second hour.
Dr Stephan Wildi and colleagues concluded, "Since rapid food intake produces more gastroesophageal reflux in healthy volunteers, studies in gastroesophageal reflux disease patients are warranted to evaluate if eating slowly may represent another "life-style modification" aimed at reducing gastroesophageal reflux".