In this study, physicians investigated the prevalence and severity of esophagitis in patients with suspected GERD-related chronic ENT symptoms.
The preformed endoscopy was performed in 405 ENT patients with suspected GERD and 545 typical GERD patients.
They determined the presence of erosive esophagitis, Barrett's esophagus, hiatal hernia, peptic ulcer, and Helicobacter pylori infection on biopsies. The results were compared with the results of a symptom questionnaire.
|Esophagitis prevalence was highest in patients with predominant cough.|
|American Journal of Gastroenterology|
The physicians found that the prevalence of erosive esophagitis and peptic ulcer was significantly higher in patients with GERD-related ENT symptoms than patients with typical GERD.
They determined that esophagitis prevalence was highest in patients with predominant cough, and lowest in globus pharyngeus and throat symptoms.
The team also found that esophagitis was associated with significantly higher rates of symptom relief during the first 8 wk of proton pump inhibitor therapy.
Dr Johan Poelmans and colleagues concluded, "Patients with suspected GERD-related ENT symptoms have a high prevalence of esophagitis and this is associated with better response to antisecretory therapy".