It remains a challenge to perform transplantation in small infants.
In this study, doctors examine their 10-year experience with liver transplantation in infants aged less than 6 months.
The team analyzed 43 patients aged 6 months or less those median weight at the time of liver transplantation was 5.8 kg.
The reasons for liver transplantation were biliary atresia, neonatal hepatitis, neonatal cholestasis, and miscellaneous.
The doctors found that patient survival was 91% after 1 year and 87% after 2 years.
In addition, graft survival was 86% after 1 year and 82% after 2 years.
Overall, acute early rejection occurred in 35% of patients, and chronic rejection in 7% of patients.
The team determined that complications such as posttransplant lymphoproliferative disease and persistent arterial hypertension were rare.
Dr Enke Grabhorn and colleagues concluded, "Liver transplantation in infants aged less than 6 months provides excellent short- and long-term results".
"Low weight or young age of infants awaiting liver transplantation should not be exclusion criteria for liver transplantation".