Intestinal transplantation may be a life-saving procedure for patients with irreversible intestinal failure who can no longer be maintained on parenteral nutrition.
In this study, doctors from Italy evaluated intestinal transplantation in patients suffering from chronic intestinal pseudo-obstruction.
The team assessed a total of 6 adult patients affected by chronic intestinal pseudo-obstruction who underwent primary intestinal transplantation, between 2000 and 2003.
|1-year patient survival = 83%.|
|American Journal of Transplantation|
They documented the patients' pre-transplant evaluation, indication for intestinal transplantation and surgical technique.
Mean follow-up was 25 months.
There were no perioperative deaths.
The team found that 5 of the 6 patients were alive at the end of follow-up.
They calculated that 1-year patient and graft survival rates were 83% and 66%, respectively.
Dr Michele Masettia's team concluded, "Our experience suggests that intestinal transplantation should be considered in adult patients suffering from chronic intestinal pseudo-obstruction and parenteral nutrition life-threatening complication".