Ischemic colitis has been associated with comorbid conditions, medications, vascular surgery and advanced age.
However, there are few data on the baseline incidence in the general population.
In this study, doctors from the United States searched bibliographic databases for studies on ischemic colitis.
|Risk was increased in females and in subjects over 65 years.|
|Alimentary Pharmacology and Therapeutics|
Studies were included if they used population-based samples, disease-specific population samples or case-control population-based samples of adults with ischemic colitis. They were also included if they reported the incidence, prevalence or risk factors for ischemic colitis.
The doctors found 4 studies that identified the general population incidence and 4 that reported the disease-specific population incidence.
They determined that the incidence of ischemic colitis in general populations ranged from 4.5 to 44 cases per 100,000 person-years.
They also found that the risk was increased 2- to 4-fold by either prevalent irritable bowel syndrome or chronic obstructive pulmonary disease.
In addition, risk was increased in females and in subjects of 65 years and older.
Dr Higgins and colleagues concluded, "Ischemic colitis is uncommon in the general population".
"The effect sizes of the most commonly reported risk factors have not been adequately quantified in population-based studies".