In this study, doctors from Hong Kong, China, evaluated 86 patients with hepatocellular carcinoma.
Patients were treated with radiofrequency ablation between 2001 and 2002.
The team divided the patients into 2 groups; those with tumors less than 3 cm in diameter (group 1) and those with tumors between 3.1 and 8 cm in diameter (group 2).
They performed radiofrequency ablation with a single or cluster cool-tip electrode.
The choice of treatment route was based on tumor size and position.
| Complete ablation was achieved in 94% of patients in group 1 and 91% of patients in group 2.|
|Archives of Surgery|
The doctors measured the rate of complication, treatment mortality, and rate of complete ablation.
They performed the radiofrequency ablation percutaneously in 26 patients in group 1 and 9 patients in group 2, and laparoscopically in 2 patients in group 1 and 1 patient in group 2. The remaining patients underwent open operation.
The team found that the complication rates were 12% in group 1 and 17% group 2. Mortality rates were 0% in group 1 and 3% in group 2.
Complete ablation, after a single session of ablation, occurred in 94% of patients in group 1 and 91% of patients in group 2.
Dr Ronnie Poon's team concluded, "Radiofrequency ablation is a safe and effective treatment for patients with hepatocellular carcinomas 3.1 to 8 cm in diameter".