In this study, researchers examined whether the incidence of intrahepatic cholangiocarcinoma (ICC) is increasing in the United States.
The team evaluated data from the Surveillance Epidemiology and End Results (SEER) program and calculated the incidence rates for ICC between 1975 and 1999.
They also noted tumor stage, microscopically confirmed cases, and the survival rates.
|Incidence increased by 165% during the study period.|
|Journal of Hepatology|
The researchers identified 2864 patients with ICC.
They determined that the incidence of ICC increased by 165% during the study period. The majority of this increase occurred after 1985.
However, there were no changes in the proportion of patients with unstaged cancer, localized cancer, microscopic confirmation, or with tumor size <5 cm.
In addition, the team found that while the 1-year survival rate increased from 16% (1975 to 1979) to 26% (1995 to1999), the 5-year survival rate remained the same.
Dr Yasser Shaib's team concluded, "The incidence of ICC continues to rise in the USA".
"The stable proportions over time of patients with early stage disease, unstaged disease, tumor size <5 cm, and microscopic confirmation suggest a true increase of ICC".