In patients with cirrhosis the implantation of a transjugular intrahepatic shunt (TIPS) results in a reduction of portal pressure. However, this intervention does not reduce mortality.
The high stenosis rates of conventional bare stents causes high reintervention rates. This may be correlated with poor survival.
ePTFE-covered stentgrafts have improved patency rates, however their impact on survival has not been ascertained.
In this study, doctors retrospectively evaluated 419 patients who received bare TIPS implantation and 89 who received ePTFE endoprostheses at centers in Austria.
|3-month survival was 93% in the ePTFE group.|
The 2 groups were compared using Kaplan-Meier and Cox regression analysis.
The doctors found that patients undergoing ePTFE stentgraft implantation had significantly higher survival rates.
They determined that 3-month survival was 93% in the ePTFE group, compared to 83%. The 1- and 2-year survival was 88% and 76% for the ePTFE-group, compared with 73% and 62% for conventional TIPS patients.
In addition, the team identified stent type, patient age, and Child-Pugh Class as independent predictors of patient survival.
Dr Bernhard Angermayr's team concluded, "Patients undergoing ePTFE-endoprosthesis implantation had higher survival rates within 2 years after TIPS-implantation".
"These data should be validated in a prospective series".