This study, in the latest issue of Alimentary Pharmacology and Therapeutics, evaluated the safety and efficacy of per-endoscopic hydrostatic balloon dilatation in patients with Crohn's disease.
A team of scientists assessed 38 patients who received balloon dilatation for intestinal symptomatic strictures. The mean length of the strictures was 2.1 cm.
|32 of the 38 patients were successfully dilated.|
|Alimentary Pharmacology and Therapeutics|
The team found that 32 of the 38 patients were successfully dilated. These patients were followed for a median of 22.8 months.
However, the team found that the probabilities of obstructive symptom recurrence were 36% at 1 year and 60% at 5 years. Overall, 12 patients had a second dilatation, and 3 a third.
The probabilities of surgery for stricture were 26% at 1 year and 43% at 5 years.
The researchers determined that the results were not altered by the age, sex, activity of the disease, passage of the stricture by the colonoscope, or by concomitant medical therapies.
Dr Sabaté's team concluded, "Hydrostatic balloon dilatation is effective for Crohn's symptomatic strictures, and can avoid or postpone surgery, with an acceptable rate of complications".