Due to the early age that pediatric patients with autoimmune hepatitis are transplanted, it is suggested that they may have different outcomes than adult. patients following liver transplantation.
Doctors in Atlanta, USA, conducted a retrospective review of 56 adult and pediatric patients who underwent liver transplantaion for autoimmune hepatitis.
Pediatric patients were over 6 times more likely to develop colitis following liver transplantation than adult patients.
Pediatric patients spent a mean of 51.7 days in hopsital compared to only 20.5 days for adult patients.
Organ rejection and recurrence of autoimmune hepatitis were determined by liver biopsy.
Patients with a rejection episode had a 1.76-fold increase in relative risk to develop autoimmune recurrence when compared to patients without rejection.
| Pediatric patients were more likely to develop ulcerative colitis following liver transplantation and they incurred longer hospital stays than adults.|