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 18 February 2018

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News

Patient responses to the handheld electronic functional dyspepsia symptom diary format

February's edition of the American Journal of Gastroenterology explores the patient responses to the handheld electronic functional dyspepsia symptom diary format.

News image

The Functional Dyspepsia Symptom Diary was developed to address the lack of symptom-focused, patient-reported outcome measures designed for use in functional dyspepsia patients and meeting Food and Drug Administration recommendations for patient-reported outcome instrument development.

Dr Fiona Taylor and colleagues from Massachusetts, USA conducted concept elicitation interviews with functional dyspepsia participants to identify symptoms important and relevant to functional dyspepsia patients.

A preliminary version of the Functional Dyspepsia Symptom Diary was constructed, then completed by functional dyspepsia participants on an electronic device in cognitive interviews to evaluate the readability, comprehensibility, relevance, and comprehensiveness of the Functional Dyspepsia Symptom Diary and to preliminarily evaluate its measurement properties.

During concept elicitation interviews, 45 participants spontaneously reported 19 symptom concepts. 


7 symptoms were selected for assessment by the 8-item Functional Dyspepsia Symptom Diary
American Journal of Gastroenterology
Of those, 7 symptoms were selected for assessment by the 8-item Functional Dyspepsia Symptom Diary.

The team reported that cognitive interviews with 57 participants confirmed participants were able to comprehend and provide meaningful responses to the Functional Dyspepsia Symptom Diary, and that the handheld electronic Functional Dyspepsia Symptom Diary format was suitable for use in the target population.

Scores of the Functional Dyspepsia Symptom Diary were well-distributed among response options, item discrimination indices suggested that the Functional Dyspepsia Symptom Diary items differentiate among patients with varying degrees of functional dyspepsia severity, and inter-item correlations suggested that no items of the Functional Dyspepsia Symptom Diary were capturing redundant information.

Dr Taylor's team commented: "The Functional Dyspepsia Symptom Diary is a content-valid patient-reported outcome measure, with preliminary psychometric evidence providing support for the Functional Dyspepsia Symptom Diary’s items and total score."

"Further psychometric evaluations are recommended to more fully test the Functional Dyspepsia Symptom Diary’s score performance and other measurement properties in the target patient population."

Am J Gastroenterol 2018: 113 (1)
06 February 2018

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