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News

Prevalence of eosinophilic gastroenteritis and colitis

November's issue of the Clinical Gastroenterology & Hepatology investigates the prevalence of eosinophilic gastroenteritis and colitis in a population-based study.

News image

Although eosinophilic esophagitis has been extensively studied, there have been few epidemiology studies of other eosinophilic gastrointestinal disorders.

Using a large, population-based database, Dr Emad Mansoor and colleagues investigated epidemiologic features of eosinophilic gastroenteritis, and eosinophilic colitis in the United State.

The researchers collected data from a commercial database that provided electronic health records from 26 major integrated U.S. healthcare systems from 1999 to 2017.

The researchers identified a cohort of adult and pediatric patients with eosinophilic gastroenteritis and eosinophilic colitis from 2012 to March 2017, based on the Systematized Nomenclature of Medicine Clinical Terms.

The team calculated the overall prevalence of eosinophilic gastroenteritis and eosinophilic colitis among different patient groups, and performed age- and gender-adjusted analyses to assess for differences in the prevalence of associated medical conditions in patients with eosinophilic gastroenteritis and eosinophilic colitis and control patients.

The overall prevalence rate of eosinophilic colitis was 2 per 100,000 persons
Clinical Gastroenterology & Hepatology

Of the 35,826,830 individuals in the database, the researchers identified 1820 patients with eosinophilic gastroenteritis and 770 with eosinophilic colitis.

The researchers noted that the overall prevalence rate of eosinophilic gastroenteritis was 5 per 100,000 persons.

The team found that the overall prevalence rate of eosinophilic colitis was 2 per 100,000 persons.

Each of the non-eosinophilic esophagitis eosinophilic gastrointestinal disorders was more prevalent in Caucasians than in African-Americans and Asians, and in female patients than male patients.

Although eosinophilic gastroenteritis was more prevalent in children than in adults, eosinophilic colitis was more prevalent in adults.

Compared with control patients, the team observed that individuals with non-eosinophilic esophagitis eosinophilic gastrointestinal disorders were more likely to have been diagnosed with other gastrointestinal or allergic disorders.

Dr Mansoor's team comments, "In a population-based study in the United States, using the Explorys database, we found the overall prevalence rate of eosinophilic gastroenteritis to be 5 per 100,000 persons and the prevalence rate of eosinophilic colitis to be 2 per 100,000."

"These values are at the lower end of prevalence rates previously reported in the United States."

Clin Gastroenterol Hepatol 2017: 15(11): 1733–1741
14 November 2017

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