A subset of patients with ulcerative colitis (UC) will require colectomy within a few years of diagnosis.
Dr Al-Darmaki and colleagues determined the clinical predictors of early colectomy among patients with UC who are hospitalized with an acute flare.
Using population-based surveillance, all adults hospitalized for UC within 3 years of diagnosis were identified.
The team's primary outcome was a colectomy within 3 years of diagnosis.
The research team reviewed all medical charts.
|Prescription of infliximab before hospitalization increased odds of surgery|
|Inflammatory Bowel Diseases|
Among patients admitted to hospital with UC within 3 years of diagnosis, the team found that 58% underwent colectomy, with the odds of colectomy decreasing by 12% per year.
The team observed that early colectomy was more likely among patients aged 35 to 64 years versus 18 to 34 years, males, those with pancolitis, and living in rural areas.
Prescription of infliximab before hospitalization increased odds of surgery.
Dr Al-Darmaki's team concludes, "Patients hospitalized for UC have a high risk of early colectomy."
"This is particularly true in middle-aged men, those living in rural areas, and those without response to infliximab."