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 25 February 2018

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News

IBD is presenting sooner after immigration in more recent immigrants from Cuba to the USA

Inflammatory bowel disease is presenting sooner after immigration in more recent US immigrants from Cuba

News image

Despite a rising incidence of inflammatory bowel disease (IBD) in Hispanics in the United States, there are no studies examining the relationship between immigrant generation and IBD onset among Hispanics.

Dr Damas and colleagues from Florida, USA determined whether age of IBD diagnosis, time from immigration to IBD diagnosis and IBD phenotype, differed across immigration periods in South Florida Cuban immigrants.

The team performed a cohort of consecutively identified Cuban-born adults who developed IBD in the United States and were followed in gastroenterology (GI) clinic.

The researchers divided time cohorts of immigration by historical relevance: before 1980, 1980-1994 and 1995-to-present.

The researchers examined differences across time cohorts in diagnosis age, time from immigration to IBD diagnosis, and IBD phenotype.

Time between immigration and diagnosis was shorter in patients arriving to the US after 1980
Alimentary Pharmacology & Therapeutics

A total of 130 Cuban patients with IBD were included.

Age of IBD diagnosis was older in Cubans arriving before 1980 than in those arriving between 1980-1994 or after 1995.

The researchers found that time between immigration and diagnosis was shorter in patients arriving to the US after 1980.

IBD phenotype, including type of IBD, disease location and surgeries, did not differ significantly across time cohorts.

Dr Damas' team concludes, "Our study describes changing patterns of IBD onset following immigration in Cubans, suggesting that environmental changes either in the United States, Cuba or both are resulting in faster IBD onset in younger immigrant generations."

"These studies can inform the search for environmental triggers that may result in IBD."

Aliment Pharmaccol Ther 2017: 46(3): 303–309
25 July 2017

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