Dr Antonio Carroccio and colleagues from Italy investigated how many patients with a diagnosis of nonceliac wheat sensitivity still experienced wheat sensitivity after a median follow-up time of 99 months.
The team collected data from 200 participants from a previous study of nonceliac wheat sensitivity, performed in 2016 in Italy.
The researchers found that 148 of these individuals were still on a strict wheat-free diet.
|98% of patients who adhered strictly to a gluten-free diet had reduced symptoms|
In total, the team noted that 88% of patients improved after a diagnosis of nonceliac wheat sensitivity.
The research team found that 98% of patients who adhered strictly to a gluten-free diet had reduced symptoms, compared with 58% of patients who did not adhere to a gluten-free diet.
Of the 22 patients who repeated the double-blind, placebo-controlled challenge, 20 reacted to wheat.
Dr Corroccio's team concludes, "Nonceliac wheat sensitivity is a persistent condition."