Infection with Giardia lamblia is a common cause of diarrheal disease in the developing and industrialized world.
Dr Benjamin Lebwohl and colleagues assessed the prevalence of giardiasis in the United States (US) among patients with duodenal biopsies, investigating demographic and clinical factors associated with this condition.
The researchers conducted a cross-sectional study of patients with duodenal biopsies submitted to a national pathology laboratory between 2008, and 2015.
The team calculated the prevalence of giardiasis and categorized it by the following patient sociodemographic and clinical data: age, sex, ethnicity, endoscopy indication, season, year, urban–rural setting, region, and presence of H. pylori and atrophic gastritis.
Among all patients, the researchers observed that the mean age was 52 years.
The prevalence of giardiasis was 0.11%.
|The prevalence of giardiasis was 0.11%|
|Digestive Diseases & Sciences|
The team found that patients with giardiasis were more likely to be male.
Among patients who had a gastric biopsy, those with giardiasis were more likely to be colonized with H. pylori.
The research team noted no statistically significant association with age, endoscopy indication, urban–rural setting, ethnicity, season, or the presence of atrophic gastritis.
The team identified that male sex, Southern region, and the presence of H. pylori were independently associated with giardiasis.
Dr Lebwohl's team concludes, "To our knowledge, this is the largest study to date to assess predictors of giardiasis in the US."
'We found that male sex, being colonized with H. pylori, and residing in the Southern US are independently associated with giardiasis infection."