Microscopic colitis is a relatively common cause of chronic watery diarrhea, especially in older persons.
Associated symptoms, including abdominal pain and arthralgias, are common.
Dr Darrell Pardi and colleagues from Minnesota, USA described the clinical features, epidemiology, pathophysiology, diagnostic criteria, and treatment of patients with microscopic colitis.
The researchers reports that the diagnosis is based upon characteristic histological findings in the presence of diarrhea.
|Only budesonide has been well studied in multiple controlled clinical trials|
|American Journal of Gastroenterology|
The 2 types of microscopic colitis, collagenous and lymphocytic colitis, share similar clinical features, with the main difference being the presence or absence of a thickened subepithelial collagen band.
The researcher notes that there are several treatment options for patients with microscopic colitis.
However, only budesonide has been well studied in multiple controlled clinical trials.
Dr Pardi concludes, "This review describes the clinical features, and treatment of microscopic colitis."