Patients with missed colorectal cancer have been reported to be more likely to have colonic diverticulosis.
Such an association could be due to either higher risk of neoplasia or difficulty examining the colon in patients with diverticulosis.
Dr Robert Sandler and colleagues from North Carolina, USA determined whether colonic diverticula are associated with an increased risk for colonic neoplasia.
The team analyzed data from a prospective study of patients undergoing screening colonoscopy that included detailed assessment of all colonic diverticula and colorectal polyps.
|35% had one or more colorectal adenomas|
|American Journal of Gastroenterology|
The researchers used logistic regression to estimate odds ratios and 95% confidence intervals while adjusting for confounding variables.
Our analyses included 624 participants.
Of these, 35% had one or more colorectal adenomas.
Diverticula on colonoscopy were not associated with an increased risk of adenomas or advanced adenomas.
Those with the greatest burden of diverticula did not have an increased risk of adenomas compared with no diverticula. Colonic diverticula were not associated with an increased risk of proximal or distal adenomas.
Dr Sandler's team concludes, "Patients with colonic diverticula do not have an increased risk of colorectal adenomas or advanced adenomas."