Body mass index (BMI) has been indicated to be associated with prognosis of acute pancreatitis.
However, the relationship between BMI and the risk of acute pancreatitis development is still unresolved.
Dr Shen Hong and colleagues examined this association by conducting a detailed meta-analysis.
The research team also assessed its prognostic role by including more researches.
|Obese patients developed significantly more complications|
|European Journal of Gastroenterology & Hepatology|
Studies were identified by searching MEDLINE and EMBASE through 2011.
The team considered 2 end points, including the risk of acute pancreatitis development, and the outcome of acute pancreatitis.
Compared with normal weight individuals, obese individuals had an increased risk of acute pancreatitis development, with significant heterogeneity among these studies.
The team found that in comparison with nonobese patients, obese patients developed significantly more severe acute pancreatitis, systemic complications, local complications, and mortality.
The researchers observed no heterogeneity among these studies.
Dr Hong's team concludes, "Findings from this meta-analysis indicated that obesity is not only associated with an increased risk of acute pancreatitis development, but it is also a poor prognostic factor for acute pancreatitis."