Dr William Leslie and colleagues from Canada clarified the role of body mass and composition as a determinant of bone mineral density in recently diagnosed inflammatory bowel disease (IBD).
The team enrolled a nested subgroup of 101 adult subjects of the population-based Manitoba Inflammatory Bowel Disease Cohort Study.
Baseline bone mineral density and body composition were measured and repeated 2 years later.
The researchers found greater weight, height, and body mass measurements were positively correlated with bone density at all sites.
Although both fat tissue and lean tissue showed positive relationships with bone mineral density, lean tissue showed a much stronger correlation than fat tissue, especially for the total hip and total body measurements.
Increase or decrease in hip bone density was strongly associated with an increase or decrease in all body mass variables, respectively.
Dr Leslie’s team concluded, “Measures of body mass are important determinants of baseline bone mineral density in recently diagnosed inflammatory bowel disease patients.”
|Fat and lean tissue were positively related with bone mineral density|
|Inflammatory Bowel Diseases|
“Furthermore, change in body mass is correlated with change in bone mineral density, especially at the total hip.”
“Early optimization and maintenance of nutrition and body weight, particularly toward lean tissue mass, may play an important role in preventing inflammatory bowel disease -related bone disease.”