Continuous intravenous administration of lidocaine may decrease the duration of ileus and pain after abdominal surgery.
Dr Marret and colleagues from the United Kingdom searched 3 databases to retrieve randomized controlled trials comparing continuous intravenous lidocaine infusion during and after abdominal surgery with placebo.
|Intravenous lidocaine decreased the duration of ileus|
|British Journal of Surgery|
The team scored study designs using the Oxford Quality Score based on randomization, double-blinding and follow-up.
Outcome measures were duration of ileus, length of hospital stay, postoperative pain, and incidence of nausea and vomiting.
The team selected 8 trials in which a total of 161 patients received intravenous lidocaine, with 159 controls.
The researchers found that intravenous lidocaine administration decreased the duration of ileus, and the incidence of nausea and vomiting.
Intravenous lidocaine also reduced the length of hospital stay, and postoperative pain intensity at 24 hours after operation on a 0-100 mm visual analogue scale.
Dr Marret’s team concluded, “Continuous intravenous administration of lidocaine during and after abdominal surgery improves patient rehabilitation and shortens hospital stay.”