Obesity has been associated with reflux esophagitis.
However, the relationship between metabolic syndrome characterised by visceral obesity and reflux esophagitis is unclear.
Dr Chung and colleagues from South Korea investigated whether metabolic syndrome or visceral obesity is a risk factor for reflux esophagitis.
The team conducted a cross-sectional study of 7078 subjects undergoing upper endoscopy during health check-ups.
|The prevalence of metabolic syndrome occurred in 27% of cases|
Of these, 3539 patients had reflux esophagitis and were compared with 750 age-, sex-, and waist circumference-matched controls who underwent abdominal computed tomography scan.
The researchers found that the prevalence of metabolic syndrome was higher in cases than controls, at 27% vs 19%, respectively.
Multivariate analysis demonstrated that metabolic syndrome is associated with reflux esophagitis.
Among the individual components of metabolic syndrome, waist circumference and triglyceride independently increased the risk for reflux esophagitis.
On sub-analysis, the research team noted that cases showed higher mean visceral adipose tissue area and subcutaneous adipose tissue area.
The team found that only visceral adipose tissue area was an independent risk factor for reflux esophagitis after adjusting for multiple confounders.
The multiple confounders included smoking, and alcohol, body mass index and subcutaneous adipose tissue area.
Dr Chung’s team concluded, “Metabolic syndrome was associated with reflux esophagitis.”
“Abdominal obesity, especially visceral obesity, was an important risk factor for reflux esophagitis.”