Compared with white individuals, black men and women have a higher incidence and mortality from colorectal cancer and may develop cancer at a younger age.
Colorectal cancer screening might be less effective in black individuals, if there are racial differences in the age-adjusted prevalence and location of cancer precursor lesions.
Dr David Lieberman and colleagues from the USA compared the prevalence rates and location of polyps sized more than 9 mm in diameter in asymptomatic black and white individuals who received colonoscopy screening.
The team collected colonoscopy data from 67 adult gastrointestinal practice sites in the United States using a computerized endoscopic report generator between 2004 and 2005.
Data were transmitted to a central data repository, where 80,061 asymptomatic white and 5464 black patients who had received screening colonoscopy were identified.
|The adjusted odds ratio for black men was 1.2|
|Journal of the American Medical Association|
The team evaluated prevalence and location of polyps sized more than 9 mm, adjusted for age, sex, and family history of colorectal cancer in a multivariate analysis.
The researchers found that both black men and women had a higher prevalence of polyps sized more than 9 mm in diameter compared with white men and women.
Compared with white patients, the adjusted odds ratio for black men was 1.2, and the adjusted odds ratio for black women was 1.6.
Black and white patients had a similar risk of proximal polyps sized more than 9 mm.
The team found, in a subanalysis of patients older than 60 years, that proximal polyps sized more than 9 mm were more likely to be prevalent in black men and women compared with white men and women.
Dr Lieberman’s team concluded, “Compared with white individuals, black men and women undergoing screening colonoscopy have a higher risk of polyps sized more than 9 mm.”
“Black individuals older than 60 years are more likely to have proximal polyps sized more than 9 mm.”