Dr Julian Perez-Palma and colleagues evaluated the impact of colorectal cancer by estimating the years of potential life lost in a cohort of patients.
The team of doctors also defined the predictive factors of years of potential life lost.
The team undertook a descriptive cross-sectional study of 980 consecutive patients.
The patients were diagnosed and treated because of colorectal cancer between 1985 and 2002.
|Male sex was an independent prognostic factor for years of potential life lost|
|European Journal of Gastroenterology & Hepatology|
Demographic, clinical, pathological, surgical, hospital stay, complications, and mortality variables were recorded.
The primary endpoint of this study was to calculate individual years of potential life lost.
The team performed univariate analysis to compare each independent variable with the variable years of potential life lost.
All clinically relevant variables associated with years of potential life lost were included in an ordinal regression model to identify independent factors prognostic of years of potential life lost.
The final study sample was 794 patients, of which 52% were men, and 48% were women, with a mean age of 65 years.
The team found that the mean global years of potential life lost for the 351 patients who died of colorectal cancer was 15 years.
Lower age, male sex, lower tumor, nodes, metastasis stage, and rectum localization of the tumor were independent prognostic factors for years of potential life lost.
Dr Perez-Palma's team concludes, "In our community, the mean number of years of potential life lost by colorectal cancer exceeds 15 years."
"Lower age, male sex, higher tumor, node, metastasis stage, and rectum localization are negative predictors of years of potential life lost."