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 24 May 2018

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News

Patient beliefs influence adherence to therapy in ulcerative colitis

The latest issue of Inflammatory Bowel Diseases investigates adherence to 5-aminosalicylic acid therapy in patients with ulcerative colitis.

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There has been a lack of qualitative research specifically in patients with inflammatory bowel disease relating to reasons for failure to take medication.

Dr Tetyana Moshkovska and colleagues from the United Kingdom identified factors which might increase adherence.

Information held by patients about ulcerative colitis impacts medication use
Inflammatory Bowel Diseases

The team recruited 27 patients from 3 hospital sites to take part in a qualitative study based on semistructured interviews.

The team explored the way in which patients appear to balance the benefits and disadvantages of taking 5-aminosalicylic acid medication.

The degree of information held by patients regarding ulcerative colitis and self-evaluation of the benefits of 5-aminosalicylic acid appears to impact whether patients accept or reject the medication.

The researchers found that decision-making on an ill-informed basis may be a factor leading to a reduction in adherence.

Due to the nature of the condition, adherence levels may be affected by potential difficulties in terms of experiencing and understanding the links between the medication and health outcomes.

Dr Moshkovska's team concluded, "Important determinants of adherence to 5-aminosalicylic acid medication in patients with ulcerative colitis appear to include the level of information provided and patient beliefs about prescribed 5-aminosalicylic acid."

"Patient adherence to 5-aminosalicylic acid requires encouragement and reinforcement and the patient-clinician relationship has a crucial role to play in this dynamic."

Inflamm Bowel Dis 2008: 14(6): 763-8
23 May 2008

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