Dr Jong Pil Im and colleagues from Korea evaluated clinical outcomes and factors associated with patency of self-expanding metal stents in patients with malignant upper gastrointestinal obstruction.
In 83 patients with malignant upper gastrointestinal obstruction, the team performed 118 self-expanding metal stents placements.
|Technical success was achieved in 99%|
|Digestive Diseases and Sciences|
The team identified obstruction sites in the esophagus/gastro-esophageal junction and gastric outlet in 41 and 42 patients, respectively.
Technical success was achieved in 99%, and clinical success in 91%, with no procedure-related complications.
The researchers found re-obstruction and migration occurred in 38% during a mean follow-up of 137 days.
Both occurred significantly more often with gastric outlet than esophageal/gastro-esophageal junction obstruction.
Patency rates of esophageal/gastro-esophageal junction obstruction were 94%, 78% and 67% at 30, 90 and 180 days, respectively.
The researchers noted that these were significantly higher than those of gastric outlet obstruction at 72%, 52% and 33%, respectively.
Palliative chemotherapy or radiation therapy was not associated with stent patency.
Dr Im's team concluded, "Endoscopic self-expanding metal stents placement is a safe and effective palliative treatment for malignant upper gastrointestinal obstruction, and complications or stent patency differed according to obstruction site."