Previous reports of liver resection for metastatic colorectal cancer are typically from single centers and cannot account for selection or referral bias.
Dr Shimul Shah and colleagues from Canada measured longterm survival after liver resection for metastatic colorectal cancer in the province of Ontario, Canada.
|The unadjusted 1-year survival after liver resection was 88%|
|Journal of the American College of Surgeons|
The Ontario Cancer Registry is an administrative database that links all hospital records, pathology reports, and vital statistics for patients with a diagnosis of cancer.
The team used the Registry to identify and obtain information on all patients who underwent liver resection for metastatic colorectal cancer in calendar years 1996 to 2004.
Pathology reports of the original colorectal cancer resection and subsequent liver resections were individually reviewed.
The team undertook 841 resections at 43 centers across Ontario during the 9-year period, including wedge resection in 36%, lobectomy in 55%, and trisectionectomy in 9%.
The research team performed 91% and 54% of resections at teaching and high-volume centers, respectively.
Most liver resections were performed more than 120 days after original colorectal cancer operation.
The research team noted that perioperative mortality was 3%.
Unadjusted 1-, 3-, and 5-year survival after liver resection was 88%, 59%, and 43%, respectively.
Survival was improved when resection was performed for fewer than 2 tumor nodules, at high-volume centers, or in the years 2001 to 2004.
Dr Shah's team concluded, "Results in this population-based series are consistent with those of single-hospital series assessing longterm survival after liver resection for metastatic colorectal cancer."
"These findings support continued efforts to aggressively identify and resect colorectal cancer liver metastases."