Diverticulosis is associated with high intracolonic pressure and a weakened bowel wall.
Chronic colitis is characterized by liquid stools suggestive of low intracolonic pressure and a thickened bowel wall.
Dr Adi Lahat and colleagues from Israel conducted a study to assess the prevalence of diverticulosis in colitis patients.
|3.5% of 1037 IBD patients had diverticuli.|
| Inflammatory Bowel Diseases |
Colonoscopy results of patients with inflammatory bowel disease (IBD)-associated colitis, older than 50 years, were retrospectively evaluated and compared with those of patients who underwent screening colonoscopy.
Only patients with biopsy-proven disease, disease duration of more than 5 years, and disease beyond the distal 20 cm were included.
In all, 1037 patients were diagnosed by colonoscopy as suffering from IBD-associated colitis between 1987-2005.
After exclusion of patients who did not meet the inclusion criteria the study population consisted of 314 IBD patients and 1023 age-matched control patients.
A significantly higher percent of diverticuli was detected in the control group compared with the IBD group (15% versus 3.5%, P <0.001).
No significant difference in the prevalence of diverticuli was detected between the three subtypes of IBD patients (2% in ulcerative colitis versus 4.7% in Crohn's colitis versus 7.6% in indeterminant colitis).
Neither disease duration nor the specific colonic segment involved had a significant influence on the prevalence of diverticulosis.
Dr Lahat concluded that, "Long-standing colonic inflammation in IBD patients is associated with a lower prevalence of diverticuli".