Available classifications of gastritis are inconsistently used.
This is possibly because none of the classifications provides immediate prognostic or therapeutic information to clinicians.
Histology reporting of hepatitis in terms of stage is clinically useful and widely accepted.
An international group operative Link on Gastritis Assessment proposed an equivalent staging system for reporting gastric histology.
Gastritis staging integrates the atrophy score, obtained by biopsy, and the atrophy topography achieved through directed biopsy mapping.
Dr Massimo Rugge and colleagues from Italy conducted a prospective cross-sectional study.
|All neoplastic lesions clustered in stages 3 to 4|
The research team assessed whether Operative Link on Gastritis Assessment staging consistently stratified patients according to their cancer risk.
The team evaluated whether this staging system provided clear prognostic or therapeutic information.
The researchers applied Operative Link on Gastritis Assessment staging for gastric cancer risk, and gastritis grading in 439 outpatients.
The patients had dyspepsia, and underwent endoscopy with standardized biopsy sampling.
Incidental neoplastic lesions and coexisting peptic ulcers were recorded.
The lesions were presented as stage, and H pylori status was recorded.
The team found that benign conditions consistently clustered in stages 0 to 2.
In contrast, the researchers observed that all neoplastic lesions clustered in stages 3 to 4.
Dr Rugge's team concluded, “Gastritis staging, combined with H pylori status, provided clinically relevant information on the overall status of the gastric mucosa with implications for prognosis, therapy and management.”