There is growing evidence that gastroesophageal reflux disease (GERD)may cause typical laryngeal/pharyngeal lesions secondary to tissue irritation.
The prevalence of those lesions in GERD patients is not well established.
Dr Stephan Vavricka and colleagues from Switzerland evaluated the prevalence of GERD signs in the laryngopharyngeal area during routine upper gastrointestinal endoscopy.
|A difference in pharyngeal wall cobblestoning was found|
|The American Journal of Gastroenterology|
Between 2000 and 2001, 1209 patients underwent 1311 upper gastrointestinal endoscopies.
The structured examination of the laryngopharyngeal area during upper gastrointestinal endoscopy was videotaped for review by 3 gastroenterologists.
Another otorhinolaryngologist blinded to the endoscopic esophageal findings reviewed the videotapes.
The research team selected 132 patients with typical endoscopical esophageal findings of GERD.
There were 132 sex- and age-matched controls who underwent upper gastrointestinal endoscopy for different reasons.
The researchers reported that controls had no reflux symptoms, and had normal esophagoscopy
The researchers found no difference in the prevalence of abnormal interarytenoid bar findings.
The team observed no differences in the prevalence of arytenoid medial wall erythema, posterior commissure changes, or posterior cricoid wall edema.
The team only noted a difference in the posterior pharyngeal wall cobblestoning.
Dr Vavricka's team concluded, "The results of this large systematic investigation challenge the diagnostic specificity of laryngopharyngeal findings attributed to gastroesophageal reflux."